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Activation of ATR-related protein kinase upon DNA damage recognition
Chromosomes are constantly damaged by exogenous and endogenous factors. To cope with DNA damage, eukaryotic cells are equipped with three phosphatidylinositol 3-kinase-related kinases (PIKKs), such as ATM, ATR, DNA-PK. PIKKs are structurally related to phosphatidylinositol 3-kinase (lipid kinase) ho...
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| Udgivet i: | Curr Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073305/ https://ncbi.nlm.nih.gov/pubmed/31624858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-019-01039-w |
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