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Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit
The microtubule-associated protein TPX2 is a key mitotic regulator that contributes through distinct pathways to spindle assembly. A well-characterised function of TPX2 is the activation, stabilisation and spindle localisation of the Aurora-A kinase. High levels of TPX2 are reported in tumours and t...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072206/ https://ncbi.nlm.nih.gov/pubmed/32041138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020374 |
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