Suppression of microtubule assembly kinetics by the mitotic protein TPX2

TPX2 is a widely conserved microtubule-associated protein that is required for mitotic spindle formation and function. Previous studies have demonstrated that TPX2 is required for the nucleation of microtubules around chromosomes; however, the molecular mechanism by which TPX2 promotes microtubule n...

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Udgivet i:J Cell Sci
Main Authors: Reid, Taylor A., Schuster, Breanna M., Mann, Barbara J., Balchand, Sai Keshavan, Plooster, Melissa, McClellan, Mark, Coombes, Courtney E., Wadsworth, Pat, Gardner, Melissa K.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852719/
https://ncbi.nlm.nih.gov/pubmed/26869224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178806
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