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Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics

Mitotic motor proteins generate force to establish and maintain spindle bipolarity, but how they are temporally and spatially regulated in vivo is unclear. Prior work demonstrated that a microtubule-associated protein, TPX2, targets kinesin-5 and kinesin-12 motors to spindle microtubules. The C-term...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Mann, Barbara J., Balchand, Sai K., Wadsworth, Patricia
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221630/
https://ncbi.nlm.nih.gov/pubmed/27852894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0476
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