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Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics

Mitotic motor proteins generate force to establish and maintain spindle bipolarity, but how they are temporally and spatially regulated in vivo is unclear. Prior work demonstrated that a microtubule-associated protein, TPX2, targets kinesin-5 and kinesin-12 motors to spindle microtubules. The C-term...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Mann, Barbara J., Balchand, Sai K., Wadsworth, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221630/
https://ncbi.nlm.nih.gov/pubmed/27852894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0476
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