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Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics

Mitotic motor proteins generate force to establish and maintain spindle bipolarity, but how they are temporally and spatially regulated in vivo is unclear. Prior work demonstrated that a microtubule-associated protein, TPX2, targets kinesin-5 and kinesin-12 motors to spindle microtubules. The C-term...

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Publicado en:Mol Biol Cell
Autores principales: Mann, Barbara J., Balchand, Sai K., Wadsworth, Patricia
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221630/
https://ncbi.nlm.nih.gov/pubmed/27852894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0476
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