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Control of Aurora-A stability through interaction with TPX2
The Aurora-A kinase has well-established roles in spindle assembly and function and is frequently overexpressed in tumours. Its abundance is cell cycle regulated, with a peak in G2 and M phases, followed by regulated proteolysis at the end of mitosis. The microtubule-binding protein TPX2 plays a maj...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Company of Biologists
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001410/ https://ncbi.nlm.nih.gov/pubmed/21147853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.075457 |
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