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Phosphatase PP2A and microtubule-mediated pulling forces disassemble centrosomes during mitotic exit

Centrosomes are microtubule-nucleating organelles that facilitate chromosome segregation and cell division in metazoans. Centrosomes comprise centrioles that organize a micron-scale mass of protein called pericentriolar material (PCM) from which microtubules nucleate. During each cell cycle, PCM acc...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Enos, Stephen J., Dressler, Martin, Gomes, Beatriz Ferreira, Hyman, Anthony A., Woodruff, Jeffrey B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829501/
https://ncbi.nlm.nih.gov/pubmed/29222174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.029777
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