Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1

Pre-mRNA encoding human NEIL1 undergoes editing by adenosine deaminase ADAR1 that converts a single adenosine to inosine, and this conversion results in an amino acid change of lysine 242 to arginine. Previous investigations of the catalytic efficiencies of the two forms of the enzyme revealed diffe...

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Détails bibliographiques
Publié dans:DNA Repair (Amst)
Auteurs principaux: Minko, Irina G., Vartanian, Vladimir L., Tozaki, Naoto N., Coskun, Erdem, Coskun, Sanem Hosbas, Jaruga, Pawel, Yeo, Jongchan, David, Sheila S., Stone, Michael P., Egli, Martin, Dizdaroglu, Miral, McCullough, Amanda K., Lloyd, R. Stephen
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069121/
https://ncbi.nlm.nih.gov/pubmed/31733589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102741
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