Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1

Pre-mRNA encoding human NEIL1 undergoes editing by adenosine deaminase ADAR1 that converts a single adenosine to inosine, and this conversion results in an amino acid change of lysine 242 to arginine. Previous investigations of the catalytic efficiencies of the two forms of the enzyme revealed diffe...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Minko, Irina G., Vartanian, Vladimir L., Tozaki, Naoto N., Coskun, Erdem, Coskun, Sanem Hosbas, Jaruga, Pawel, Yeo, Jongchan, David, Sheila S., Stone, Michael P., Egli, Martin, Dizdaroglu, Miral, McCullough, Amanda K., Lloyd, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7069121/
https://ncbi.nlm.nih.gov/pubmed/31733589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102741
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