An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers

BACKGROUND: BRCA1/2 germline mutation related cancers are candidates for new immune therapeutic interventions. This study was a hypothesis generating exploration of genomic data collected at diagnosis for 19 patients. The prominent tumor mutation burden (TMB) in hereditary breast and ovarian cancers...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Cancer
Egile Nagusiak: Przybytkowski, Ewa, Davis, Thomas, Hosny, Abdelrahman, Eismann, Julia, Matulonis, Ursula A., Wulf, Gerburg M., Nabavi, Sheida
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068944/
https://ncbi.nlm.nih.gov/pubmed/32164626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6605-1
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