Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

BACKGROUND: Approximately 8–15% epithelial ovarian cancer patients are BRCA1 or BRCA2 germline mutation carriers. Brazilian inhabitants may have peculiar genetic characteristics associated with ethnic diversity, and studies focusing on the entire BRCA1/BRCA2 gene sequencing in Brazilian ovarian canc...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Maistro, Simone, Teixeira, Natalia, Encinas, Giselly, Katayama, Maria Lucia Hirata, Niewiadonski, Vivian Dionisio Tavares, Cabral, Larissa Garcia, Ribeiro, Roberto Marques, Gaburo Junior, Nelson, de Gouvêa, Ana Carolina Ribeiro Chaves, Carraro, Dirce Maria, Sabino, Ester Cerdeira, Diz, Maria del Pilar Estevez, Chammas, Roger, de Bock, Geertruida Hendrika, Folgueira, Maria Aparecida Azevedo Koike
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135756/
https://ncbi.nlm.nih.gov/pubmed/27914478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2966-x
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