Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil

BACKGROUND: Approximately 8–15% epithelial ovarian cancer patients are BRCA1 or BRCA2 germline mutation carriers. Brazilian inhabitants may have peculiar genetic characteristics associated with ethnic diversity, and studies focusing on the entire BRCA1/BRCA2 gene sequencing in Brazilian ovarian canc...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Maistro, Simone, Teixeira, Natalia, Encinas, Giselly, Katayama, Maria Lucia Hirata, Niewiadonski, Vivian Dionisio Tavares, Cabral, Larissa Garcia, Ribeiro, Roberto Marques, Gaburo Junior, Nelson, de Gouvêa, Ana Carolina Ribeiro Chaves, Carraro, Dirce Maria, Sabino, Ester Cerdeira, Diz, Maria del Pilar Estevez, Chammas, Roger, de Bock, Geertruida Hendrika, Folgueira, Maria Aparecida Azevedo Koike
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135756/
https://ncbi.nlm.nih.gov/pubmed/27914478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2966-x
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