Nalaganje...
Organocatalytic Enantioselective Conjugate Addition of Nitromethane to Benzylidene-2-Benzoyl Acetate: Asymmetric Synthesis of ABT – 627, an Endothelin Receptor Antagonist
First catalytic and enantioselective conjugate addition of nitromethane to benzylidene-2-benzoyl acetate has been developed using dihydroquinine derived squaramide catalyst with moderate to high selectivities. Asymmetric total synthesis of ABT-627, a potent ETA receptor antagonist is accomplished ut...
Shranjeno v:
| izdano v: | Front Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066299/ https://ncbi.nlm.nih.gov/pubmed/32195223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00135 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|