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Salmonella-driven polarization of granuloma macrophages antagonizes TNF-mediated pathogen restriction during persistent infection

Many intracellular bacteria can establish chronic infection and persist in tissues within granulomas comprised of macrophages. Granuloma macrophages exhibit heterogeneous polarization states, or phenotypes, that may be functionally distinct. Here, we elucidate a host-pathogen interaction that contro...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cell Host Microbe
Päätekijät: Pham, Trung H. M., Brewer, Susan M., Thurston, Teresa, Massis, Liliana M., Honeycutt, Jared, Lugo, Kyler, Jacobson, Amanda R., Vilches-Moure, Jose G., Hamblin, Meagan, Helaine, Sophie, Monack, Denise M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065835/
https://ncbi.nlm.nih.gov/pubmed/31883922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.11.011
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