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Salmonella-driven polarization of granuloma macrophages antagonizes TNF-mediated pathogen restriction during persistent infection

Many intracellular bacteria can establish chronic infection and persist in tissues within granulomas comprised of macrophages. Granuloma macrophages exhibit heterogeneous polarization states, or phenotypes, that may be functionally distinct. Here, we elucidate a host-pathogen interaction that contro...

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Bibliografische gegevens
Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Pham, Trung H. M., Brewer, Susan M., Thurston, Teresa, Massis, Liliana M., Honeycutt, Jared, Lugo, Kyler, Jacobson, Amanda R., Vilches-Moure, Jose G., Hamblin, Meagan, Helaine, Sophie, Monack, Denise M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065835/
https://ncbi.nlm.nih.gov/pubmed/31883922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.11.011
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