Salmonella-driven polarization of granuloma macrophages antagonizes TNF-mediated pathogen restriction during persistent infection

Many intracellular bacteria can establish chronic infection and persist in tissues within granulomas comprised of macrophages. Granuloma macrophages exhibit heterogeneous polarization states, or phenotypes, that may be functionally distinct. Here, we elucidate a host-pathogen interaction that contro...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Pham, Trung H. M., Brewer, Susan M., Thurston, Teresa, Massis, Liliana M., Honeycutt, Jared, Lugo, Kyler, Jacobson, Amanda R., Vilches-Moure, Jose G., Hamblin, Meagan, Helaine, Sophie, Monack, Denise M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065835/
https://ncbi.nlm.nih.gov/pubmed/31883922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.11.011
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