Salmonella-driven polarization of granuloma macrophages antagonizes TNF-mediated pathogen restriction during persistent infection

Many intracellular bacteria can establish chronic infection and persist in tissues within granulomas comprised of macrophages. Granuloma macrophages exhibit heterogeneous polarization states, or phenotypes, that may be functionally distinct. Here, we elucidate a host-pathogen interaction that contro...

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Bibliografiska uppgifter
I publikationen:Cell Host Microbe
Huvudupphovsmän: Pham, Trung H. M., Brewer, Susan M., Thurston, Teresa, Massis, Liliana M., Honeycutt, Jared, Lugo, Kyler, Jacobson, Amanda R., Vilches-Moure, Jose G., Hamblin, Meagan, Helaine, Sophie, Monack, Denise M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065835/
https://ncbi.nlm.nih.gov/pubmed/31883922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.11.011
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