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Pseudogenization of the secreted effector gene sseI confers rapid systemic dissemination of S. Typhimurium ST313 within migratory dendritic cells

Genome degradation correlates with host adaptation and systemic disease in Salmonella. Most lineages of the S. enterica subspecies Typhimurium cause gastroenteritis in humans, however, the recently emerged ST313 lineage II pathovar commonly causes systemic bacteremia in sub-Saharan Africa. ST313 lin...

詳細記述

保存先:
書誌詳細
出版年:Cell Host Microbe
主要な著者: Carden, Sarah E., Walker, Gregory T., Honeycutt, Jared, Lugo, Kyler, Pham, Trung, Jacobson, Amanda, Bouley, Donna, Idoyaga, Juliana, Tsolis, Renee M., Monack, Denise
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325708/
https://ncbi.nlm.nih.gov/pubmed/28182950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.01.009
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