Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

Dendritic cells (DCs) are specialized antigen presenting cells that instruct T cell responses through sensing environmental and inflammatory danger signals. Maintaining the homeostasis of the multiple functionally distinct conventional dendritic cells (cDC) subsets that exist in vivo is crucial for...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Purvis, Harriet A., Clarke, Fiona, Montgomery, Anna B., Colas, Chloe, Bibby, Jack A., Cornish, Georgina H., Dai, Xuezhi, Dudziak, Diana, Rawlings, David J., Zamoyska, Rose, Guermonprez, Pierre, Cope, Andrew P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065600/
https://ncbi.nlm.nih.gov/pubmed/32194571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00376
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