Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway

Dimethyl itaconate (DI) is a membrane‐permeable itaconate derivative with anti‐inflammatory functions. However, the anti‐inflammatory effect of DI has never been studied in fungal keratitis. In this study, we tested the protective effect of DI against fungal keratitis and assessed the role of NF‐E2‐...

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Publicado en:Immunol Cell Biol
Autores principales: Gu, Lingwen, Lin, Jing, Wang, Qian, Li, Cui, Peng, Xudong, Fan, Yiqun, Lu, Chunli, Lin, Hao, Niu, Yawen, Zhu, Guoqiang, Zhao, Guiqiu
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065235/
https://ncbi.nlm.nih.gov/pubmed/31943336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12316
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