Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly

Itaconic acid is an important metabolite produced by macrophages after stimulation with LPS. The role of itaconate in the inflammatory cascade is unclear. Here we used [(13)C]itaconate and dimethyl [(13)C]itaconate (DMI) to probe itaconate metabolism, and find that [(13)C]DMI is not metabolized to i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: ElAzzouny, Mahmoud, Tom, Christopher T. M. B., Evans, Charles R., Olson, Lori L., Tanga, Mary J., Gallagher, Katherine A., Martin, Brent R., Burant, Charles F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Accelerated Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377792/
https://ncbi.nlm.nih.gov/pubmed/28188288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.775270
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados