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Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly
Itaconic acid is an important metabolite produced by macrophages after stimulation with LPS. The role of itaconate in the inflammatory cascade is unclear. Here we used [(13)C]itaconate and dimethyl [(13)C]itaconate (DMI) to probe itaconate metabolism, and find that [(13)C]DMI is not metabolized to i...
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| Wydane w: | J Biol Chem |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5377792/ https://ncbi.nlm.nih.gov/pubmed/28188288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.775270 |
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