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Increased Glucose Metabolism and Glycerolipid Formation by Fatty Acids and GPR40 Receptor Signaling Underlies the Fatty Acid Potentiation of Insulin Secretion

Acute fatty acid (FA) exposure potentiates glucose-stimulated insulin secretion in β cells through metabolic and receptor-mediated effects. We assessed the effect of fatty acids on the dynamics of the metabolome in INS-1 cells following exposure to [U-(13)C]glucose to assess flux through metabolic p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: El-Azzouny, Mahmoud, Evans, Charles R., Treutelaar, Mary K., Kennedy, Robert T., Burant, Charles F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036363/
https://ncbi.nlm.nih.gov/pubmed/24675078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.531970
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