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Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway

Dimethyl itaconate (DI) is a membrane‐permeable itaconate derivative with anti‐inflammatory functions. However, the anti‐inflammatory effect of DI has never been studied in fungal keratitis. In this study, we tested the protective effect of DI against fungal keratitis and assessed the role of NF‐E2‐...

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Detalles Bibliográficos
Publicado en:Immunol Cell Biol
Main Authors: Gu, Lingwen, Lin, Jing, Wang, Qian, Li, Cui, Peng, Xudong, Fan, Yiqun, Lu, Chunli, Lin, Hao, Niu, Yawen, Zhu, Guoqiang, Zhao, Guiqiu
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065235/
https://ncbi.nlm.nih.gov/pubmed/31943336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12316
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