Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway

Dimethyl itaconate (DI) is a membrane‐permeable itaconate derivative with anti‐inflammatory functions. However, the anti‐inflammatory effect of DI has never been studied in fungal keratitis. In this study, we tested the protective effect of DI against fungal keratitis and assessed the role of NF‐E2‐...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Gu, Lingwen, Lin, Jing, Wang, Qian, Li, Cui, Peng, Xudong, Fan, Yiqun, Lu, Chunli, Lin, Hao, Niu, Yawen, Zhu, Guoqiang, Zhao, Guiqiu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065235/
https://ncbi.nlm.nih.gov/pubmed/31943336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12316
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