Perillaldehyde Ameliorates Aspergillus fumigatus Keratitis by Activating the Nrf2/HO-1 Signaling Pathway and Inhibiting Dectin-1-Mediated Inflammation

PURPOSE: The purpose of this study was to investigate the therapeutic effect of perillaldehyde (PAE) on Aspergillus fumigatus (A. fumigatus) keratitis. METHODS: Human corneal epithelial cells (HCECs) were pretreated with PAE and stimulated with A. fumigatus mycelium. C57BL/6 mice were infected with...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Invest Ophthalmol Vis Sci
Prif Awduron: Fan, Yiqun, Li, Cui, Peng, Xudong, Jiang, Nan, Hu, Liting, Gu, Lingwen, Zhu, Guoqiang, Zhao, Guiqiu, Lin, Jing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2020
Pynciau:
Cornea
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415897/
https://ncbi.nlm.nih.gov/pubmed/32579678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.51
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