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Picolinic Acid, a Tryptophan Oxidation Product, does not Impact Bone Mineral Density but Increases Marrow Adiposity

Tryptophan is an essential amino acid catabolized initially to kynurenine (kyn), an immunomodulatory metabolite that we have previously shown to promote bone loss. Kyn levels increase with aging and have also been associated with neurodegenerative disorders. Picolinic acid (PA) is another tryptophan...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Exp Gerontol
Main Authors: Ding, Kehong, McGee-Lawrence, Meghan E., Kaiser, Helen, Sharma, Anuj K., Pierce, Jessica L., Irsik, Debra L., Bollag, Wendy B., Xu, Jianrui, Zhong, Qing, Hill, William, Shi, Xing-Ming, Fulzele, Sadanand, Kennedy, Eileen J., Elsalanty, Mohammed, Hamrick, Mark W., Isales, Carlos M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065047/
https://ncbi.nlm.nih.gov/pubmed/32088397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2020.110885
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