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Synthesis and Biological Characterization of Monomeric and Tetrameric RGD‐Cryptophycin Conjugates
The effective delivery of cytotoxic agents to tumor cells is a key challenge in anticancer therapy. Multivalent integrinspecific ligands are considered a promising tool to increase the binding affinity, selectivity, and internalization efficiency of small‐molecule drug conjugates. Herein, we report...
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| Publicado en: | Chemistry |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7064988/ https://ncbi.nlm.nih.gov/pubmed/31943410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905437 |
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