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In Vivo Antitumor Activity of a Novel Acetazolamide–Cryptophycin Conjugate for the Treatment of Renal Cell Carcinomas

[Image: see text] Traditional chemotherapeutics used in cancer therapy do not preferentially accumulate in tumor tissues. The conjugation to delivery vehicles like antibodies or small molecules has been proposed as a strategy to increase the tumor uptake and improve the therapeutic window of these d...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Cazzamalli, Samuele, Figueras, Eduard, Pethő, Lilla, Borbély, Adina, Steinkühler, Christian, Neri, Dario, Sewald, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276201/
https://ncbi.nlm.nih.gov/pubmed/30533574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b02350
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