Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination

Innovative and efficient hit‐identification techniques are required to accelerate drug discovery. Protein‐templated fragment ligations represent a promising strategy in early drug discovery, enabling the target to assemble and select its binders from a pool of building blocks. Development of new pro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:ChemMedChem
Päätekijät: van der Vlag, Ramon, Yagiz Unver, M., Felicetti, Tommaso, Twarda‐Clapa, Aleksandra, Kassim, Fatima, Ermis, Cagdas, Neochoritis, Constantinos G., Musielak, Bogdan, Labuzek, Beata, Dömling, Alexander, Holak, Tad A., Hirsch, Anna K. H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Full Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064911/
https://ncbi.nlm.nih.gov/pubmed/31774938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900574
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