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A benchmark of algorithms for the analysis of pooled CRISPR screens
Genome-wide pooled CRISPR-Cas-mediated knockout, activation, and repression screens are powerful tools for functional genomic investigations. Despite their increasing importance, there is currently little guidance on how to design and analyze CRISPR-pooled screens. Here, we provide a review of the c...
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| Veröffentlicht in: | Genome Biol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063732/ https://ncbi.nlm.nih.gov/pubmed/32151271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01972-x |
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