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Pooled CRISPR screens in Drosophila cells

High-throughput screens in Drosophila cell lines have led to discovery of conserved gene functions related to signal transduction, host-pathogen interactions, ion transport, and more. CRISPR/Cas9 technology has opened the door to new types of large-scale cell-based screens. Whereas arrayed-format sc...

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Dettagli Bibliografici
Pubblicato in:Curr Protoc Mol Biol
Autori principali: Viswanatha, Raghuvir, Brathwaite, Roderick, Hu, Yanhui, Li, Zhongchi, Rodiger, Jonathan, Merckaert, Pierre, Chung, Verena, Mohr, Stephanie E., Perrimon, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961806/
https://ncbi.nlm.nih.gov/pubmed/31763777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpmb.111
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