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Kinetics of CXCL12 binding to atypical chemokine receptor 3 reveal a role for the receptor N-terminus in chemokine binding
Chemokines bind to membrane-spanning chemokine receptors, which signal through G proteins and promote cell migration. However, the atypical chemokine receptor 3 (ACKR3) does not appear to couple to G proteins and instead of directly promoting cell migration, it regulates the extracellular concentrat...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063449/ https://ncbi.nlm.nih.gov/pubmed/31506383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaw3657 |
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