Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques

Intraplaque hemorrhage frequently occurs in atherosclerotic plaques resulting in cell-free hemoglobin, which is oxidized to ferryl hemoglobin (FHb) in the highly oxidative environment. Osteoclast-like cells (OLCs) derived from macrophages signify a counterbalance mechanism for calcium deposition in...

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Pubblicato in:Oxid Med Cell Longev
Autori principali: Zavaczki, Erzsébet, Gáll, Tamás, Zarjou, Abolfazl, Hendrik, Zoltán, Potor, László, Tóth, Csaba Zsigmond, Méhes, Gábor, Gyetvai, Ágnes, Agarwal, Anupam, Balla, György, Balla, József
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063196/
https://ncbi.nlm.nih.gov/pubmed/32184915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3721383
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