Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease

Aims: Airway and pulmonary vascular remodeling is an important pathological feature in the pathogenesis of chronic obstructive pulmonary disease (COPD). Tobacco smoke (TS) induces the production of large amounts of reactive oxygen species (ROS) in COPD lungs. We investigated how ROS lead to airway a...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Zhu, Jing, Kovacs, Laszlo, Han, Weihong, Liu, Guojun, Huo, Yuqing, Lucas, Rudolf, Fulton, David, Greer, Peter A., Su, Yunchao
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Forum Original Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061305/
https://ncbi.nlm.nih.gov/pubmed/31088299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7648
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