Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease

Aims: Airway and pulmonary vascular remodeling is an important pathological feature in the pathogenesis of chronic obstructive pulmonary disease (COPD). Tobacco smoke (TS) induces the production of large amounts of reactive oxygen species (ROS) in COPD lungs. We investigated how ROS lead to airway a...

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Dettagli Bibliografici
Pubblicato in:Antioxid Redox Signal
Autori principali: Zhu, Jing, Kovacs, Laszlo, Han, Weihong, Liu, Guojun, Huo, Yuqing, Lucas, Rudolf, Fulton, David, Greer, Peter A., Su, Yunchao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2019
Soggetti:
Forum Original Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061305/
https://ncbi.nlm.nih.gov/pubmed/31088299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7648
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