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Calpain-2 activates Akt via TGF-β(1)-mTORC2 pathway in pulmonary artery smooth muscle cells
Calpain is a family of calcium-dependent nonlysosomal neutral cysteine endopeptidases. Akt is a serine/threonine kinase that belongs to AGC kinases and plays important roles in cell survival, growth, proliferation, angiogenesis, and cell metabolism. Both calpain and Akt are the downstream signaling...
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| Publicado no: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967130/ https://ncbi.nlm.nih.gov/pubmed/27099352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00295.2015 |
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