Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension

Calpain mediates collagen synthesis and cell proliferation and plays an important role in pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). In the present study, we investigated whether and how calpain is activated by PAH mediators in pulmonary artery smooth muscle cells (PASMC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Kovacs, Laszlo, Han, Weihong, Rafikov, Ruslan, Bagi, Zsolt, Offermanns, Stefan, Saido, Takaomi C., Black, Stephen M., Su, Yunchao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821035/
https://ncbi.nlm.nih.gov/pubmed/26248159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0151OC
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