Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension

Calpain mediates collagen synthesis and cell proliferation and plays an important role in pulmonary vascular remodeling in pulmonary arterial hypertension (PAH). In the present study, we investigated whether and how calpain is activated by PAH mediators in pulmonary artery smooth muscle cells (PASMC...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Cell Mol Biol
Asıl Yazarlar: Kovacs, Laszlo, Han, Weihong, Rafikov, Ruslan, Bagi, Zsolt, Offermanns, Stefan, Saido, Takaomi C., Black, Stephen M., Su, Yunchao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821035/
https://ncbi.nlm.nih.gov/pubmed/26248159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0151OC
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