Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease

Aims: Airway and pulmonary vascular remodeling is an important pathological feature in the pathogenesis of chronic obstructive pulmonary disease (COPD). Tobacco smoke (TS) induces the production of large amounts of reactive oxygen species (ROS) in COPD lungs. We investigated how ROS lead to airway a...

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Publicat a:Antioxid Redox Signal
Autors principals: Zhu, Jing, Kovacs, Laszlo, Han, Weihong, Liu, Guojun, Huo, Yuqing, Lucas, Rudolf, Fulton, David, Greer, Peter A., Su, Yunchao
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2019
Matèries:
Forum Original Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061305/
https://ncbi.nlm.nih.gov/pubmed/31088299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7648
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