Reactive Oxygen Species-Dependent Calpain Activation Contributes to Airway and Pulmonary Vascular Remodeling in Chronic Obstructive Pulmonary Disease

Aims: Airway and pulmonary vascular remodeling is an important pathological feature in the pathogenesis of chronic obstructive pulmonary disease (COPD). Tobacco smoke (TS) induces the production of large amounts of reactive oxygen species (ROS) in COPD lungs. We investigated how ROS lead to airway a...

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Vydáno v:Antioxid Redox Signal
Hlavní autoři: Zhu, Jing, Kovacs, Laszlo, Han, Weihong, Liu, Guojun, Huo, Yuqing, Lucas, Rudolf, Fulton, David, Greer, Peter A., Su, Yunchao
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc., publishers 2019
Témata:
Forum Original Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061305/
https://ncbi.nlm.nih.gov/pubmed/31088299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7648
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