Selective BCL-X(L) inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells

BACKGROUND: CNS tumors, including medulloblastoma and pediatric glioblastoma (pGBM) account for the majority of solid pediatric malignancies. There remains an unmet need to identify novel treatment approaches in poor prognosis and relapsed pediatric brain tumors, where therapeutic options are limite...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Levesley, Jane, Steele, Lynette, Brüning-Richardson, Anke, Davison, Adam, Zhou, Jia, Ding, Chunyong, Lawler, Sean, Short, Susan C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Basic and Translational Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059858/
https://ncbi.nlm.nih.gov/pubmed/29016820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox134
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg