Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway

由 Ding, Chunyong, Song, Zilan, Shen, Ancheng, Chen, Tingting, Zhang, Ao
發表在 Acta Pharm Sin B (2020)

Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury

由 Ding, Chunyong, Chen, Hongjin, Liang, Bin, Jiao, Mingkun, Liang, Guang, Zhang, Ao
發表在 Chem Sci (2019)

Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product

由 Zhao, Hongchuan, Sun, Pu, Guo, Wei, Wang, Yi, Zhang, Ao, Meng, Linghua, Ding, Chunyong
發表在 Molecules (2019)

Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist

由 Chen, Haijun, Ding, Chunyong, Wild, Christopher, Liu, Huiling, Wang, Tianzhi, White, Mark A., Cheng, Xiaodong, Zhou, Jia
出版 2013

Overcoming Synthetic Challenges of Oridonin A-Ring Structural Diversification: Regio- and Stereoselective Installation of Azides and 1,2,3-Triazoles at the C-1, C-2, or C-3 Positio...

由 Ding, Chunyong, Zhang, Yusong, Chen, Haijun, Wild, Christopher, Wang, Tianzhi, White, Mark A., Shen, Qiang, Zhou, Jia
出版 2013

Discovery of O-Alkylamino-Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents

由 Chen, Haijun, Yang, Zhengduo, Ding, Chunyong, Chu, Lili, Zhang, Yusong, Terry, Kristin, Liu, Huiling, Shen, Qiang, Zhou, Jia
出版 2013

Novel Nitrogen-Enriched Oridonin Analogs with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility

由 Ding, Chunyong, Zhang, Yusong, Chen, Haijun, Yang, Zhengduo, Wild, Christopher, Chu, Lili, Liu, Huiling, Shen, Qiang, Zhou, Jia
出版 2013

A Combined Bioinformatics and Chemoinformatics Approach for Developing Asymmetric Bivalent AMPA Receptor Positive Allosteric Modulators as Neuroprotective Agents

由 Chen, Haijun, Wang, Cheng Z., Ding, Chunyong, Wild, Christopher, Copits, Bryan, Swanson, Geoffrey T., Johnson, Kenneth M., Zhou, Jia
出版 2012

Fragment-based drug design and identification of HJC0123, a novel orally bioavailable STAT3 inhibitor for cancer therapy

由 Chen, Haijun, Yang, Zhengduo, Ding, Chunyong, Chu, Lili, Zhang, Yusong, Terry, Kristin, Liu, Huiling, Shen, Qiang, Zhou, Jia
出版 2013

Oridonin Inhibits Hepatic Stellate Cell Proliferation and Fibrogenesis

由 Bohanon, Fredrick J., Wang, Xiaofu, Ding, Chunyong, Ding, Ye, Radhakrishnan, Geetha L., Rastellini, Cristiana, Zhou, Jia, Radhakrishnan, Ravi S.
發表在 J Surg Res (2014)

Enhanced Effects of Novel Oridonin Analog CYD0682 for Hepatic Fibrosis

由 Bohanon, Fredrick J., Wang, Xiaofu, Graham, Brittany M., Ding, Chunyong, Ding, Ye, Rastellini, Cristiana, Zhou, Jia, Radhakrishnan, Ravi S.
發表在 J Surg Res (2015)

Selective BCL-X(L) inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells

由 Levesley, Jane, Steele, Lynette, Brüning-Richardson, Anke, Davison, Adam, Zhou, Jia, Ding, Chunyong, Lawler, Sean, Short, Susan C
發表在 Neuro Oncol (2018)

Exploration of Synthetic Approaches and Pharmacological Evaluation of PNU-69176E and Its Stereoisomer as 5-HT(2C) Receptor Allosteric Modulators

由 Ding, Chunyong, Bremer, Nicole M., Smith, Thressa D., Seitz, Patricia K., Anastasio, Noelle C., Cunningham, Kathryn A., Zhou, Jia
出版 2012

Discovery and development of natural product oridonin-inspired anticancer agents

由 Ding, Ye, Ding, Chunyong, Ye, Na, Liu, Zhiqing, Wold, Eric A., Chen, Haiying, Wild, Christopher, Shen, Qiang, Zhou, Jia
發表在 Eur J Med Chem (2016)

Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma

由 Liu, Xiaohua, Zhang, Yu, Li, Yalei, Wang, Juan, Ding, Huaqian, Huang, Wenjing, Ding, Chunyong, Liu, Hongchun, Tan, Wenfu, Zhang, Ao
發表在 Acta Pharm Sin B (2021)

ent-Kaurane-Based Regio- and Stereoselective Inverse Electron Demand Hetero-Diels-Alder Reactions: Synthesis of Dihydropyran-Fused Diterpenoids()

由 Ding, Chunyong, Wang, Lili, Chen, Haijun, Wild, Christopher, Ye, Na, Ding, Ye, Wang, Tianzhi, White, Mark A., Shen, Qiang, Zhou, Jia
出版 2014

Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines

由 Rudra, Jai S., Ding, Ye, Neelakantan, Harshini, Ding, Chunyong, Appavu, Rajagopal, Stutz, Sonja, Snook, Joshua D., Chen, Haiying, Cunningham, Kathryn A., Zhou, Jia
發表在 ACS Chem Neurosci (2016)

Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo

由 Chen, Haijun, Mrazek, Amy A., Wang, Xiaofu, Ding, Chunyong, Ding, Ye, Porro, Laura J., Liu, Huiling, Chao, Celia, Hellmich, Mark R., Zhou, Jia
出版 2014

Oridonin Ring A-Based Diverse Constructions of Enone Functionality: Identification of Novel Dienone Analogues Effective for Highly Aggressive Breast Cancer by Inducing Apoptosis

由 Ding, Chunyong, Zhang, Yusong, Chen, Haijun, Yang, Zhengduo, Wild, Christopher, Ye, Na, Ester, Corbin D., Xiong, Ailian, White, Mark A., Shen, Qiang, Zhou, Jia
出版 2013

Regio- and Stereospecific Synthesis of Oridonin D‑Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads

由 Ding, Ye, Li, Dengfeng, Ding, Chunyong, Wang, Pingyuan, Liu, Zhiqing, Wold, Eric A., Ye, Na, Chen, Haiying, White, Mark A., Shen, Qiang, Zhou, Jia
發表在 J Med Chem (2018)