Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma

Medulloblastoma (MB) is a common yet highly heterogeneous childhood malignant brain tumor, however, clinically effective molecular targeted therapy is lacking. Modulation of hedgehog (HH) signaling by epigenetically targeting the transcriptional factors GLI through bromodomain-containing protein 4 (...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Acta Pharm Sin B
Κύριοι συγγραφείς: Liu, Xiaohua, Zhang, Yu, Li, Yalei, Wang, Juan, Ding, Huaqian, Huang, Wenjing, Ding, Chunyong, Liu, Hongchun, Tan, Wenfu, Zhang, Ao
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Elsevier 2021
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893122/
https://ncbi.nlm.nih.gov/pubmed/33643826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.07.007
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια