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Efficient Synthesis of ESI-09, A Novel Non-cyclic Nucleotide EPAC Antagonist
A concise and efficient synthetic approach to producing a novel non-cyclic nucleotide EPAC antagonist ESI-09 and its new analogs is reported. Key features of the synthesis include a mild and reliable one-pot procedure for an isoxazole synthon, as well as a modified one-pot protocol for the cyanometh...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3580859/ https://ncbi.nlm.nih.gov/pubmed/23459418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.01.024 |
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