OP33 GLYCOGEN SYNTHASE KINASE INHIBITORS REDUCE 3D MIGRATION OF PATIENT DERIVED GLIOBLASTOMA MULTIFORME STEM CELLS

INTRODUCTION: Glioblastoma multiforme (GBM) is a fast growing, highly invasive malignant brain tumour. Inhibition of tumour cell migration into normal brain tissue represents a major target for treatment. Glycogen synthase kinase (GSK-3) inhibition has been associated with reduced GBM invasion in in...

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Main Authors: Tams, Daniel M., Murray, Clare, Barry, Simon T., Lawler, Sean, Bruning-Richardson, Anke, Short, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200977/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou251.31
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