Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was...

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Bibliographische Detailangaben
Veröffentlicht in:Neural Regen Res
Hauptverfasser: Zhang, Yan, Fan, Bao-You, Pang, Yi-Lin, Shen, Wen-Yuan, Wang, Xu, Zhao, Chen-Xi, Li, Wen-Xiang, Liu, Chang, Kong, Xiao-Hong, Ning, Guang-Zhi, Feng, Shi-Qing, Yao, Xue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wolters Kluwer - Medknow 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059591/
https://ncbi.nlm.nih.gov/pubmed/31997820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.274344
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