Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was...

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Bibliographic Details
Published in:Neural Regen Res
Main Authors: Zhang, Yan, Fan, Bao-You, Pang, Yi-Lin, Shen, Wen-Yuan, Wang, Xu, Zhao, Chen-Xi, Li, Wen-Xiang, Liu, Chang, Kong, Xiao-Hong, Ning, Guang-Zhi, Feng, Shi-Qing, Yao, Xue
Format: Artigo
Language:Inglês
Published: Wolters Kluwer - Medknow 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059591/
https://ncbi.nlm.nih.gov/pubmed/31997820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.274344
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