Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4

Our previous studies showed that ferroptosis plays an important role in the acute and subacute stages of spinal cord injury. High intracellular iron levels and low glutathione levels make oligodendrocytes vulnerable to cell death after central nervous system trauma. In this study, we established an...

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Main Authors: Bao-You Fan, Yi-Lin Pang, Wen-Xiang Li, Chen-Xi Zhao, Yan Zhang, Xu Wang, Guang-Zhi Ning, Xiao-Hong Kong, Chang Liu, Xue Yao, Shi-Qing Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2021-01-01
Colecção:Neural Regeneration Research
Assuntos:
cell death; central nervous system; factor; ferroptosis; oligodendrocyte; oxidation; pathway; repair; spinal cord injury
Acesso em linha:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=3;spage=561;epage=566;aulast=Fan
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