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Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was...

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Podrobná bibliografie
Vydáno v:Neural Regen Res
Hlavní autoři: Zhang, Yan, Fan, Bao-You, Pang, Yi-Lin, Shen, Wen-Yuan, Wang, Xu, Zhao, Chen-Xi, Li, Wen-Xiang, Liu, Chang, Kong, Xiao-Hong, Ning, Guang-Zhi, Feng, Shi-Qing, Yao, Xue
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer - Medknow 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059591/
https://ncbi.nlm.nih.gov/pubmed/31997820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.274344
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