Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury. However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell death. By comparing the survival rate and morphology of primary neurons and SH-SY5Y cells exposed to erastin, it was...

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Detalhes bibliográficos
Publicado no:Neural Regen Res
Main Authors: Zhang, Yan, Fan, Bao-You, Pang, Yi-Lin, Shen, Wen-Yuan, Wang, Xu, Zhao, Chen-Xi, Li, Wen-Xiang, Liu, Chang, Kong, Xiao-Hong, Ning, Guang-Zhi, Feng, Shi-Qing, Yao, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059591/
https://ncbi.nlm.nih.gov/pubmed/31997820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.274344
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