Mitochondrial damage and activation of the STING pathway leads to renal inflammation and fibrosis

Fibrosis of the kidney is the final common pathway leading to end stage renal failure. By analyzing kidneys of patients and animal models with fibrosis we observed a significant mitochondrial defect, including the loss of the mitochondrial transcription factor A (TFAM) in kidney tubule cells. Here,...

詳細記述

保存先:
書誌詳細
出版年:Cell Metab
主要な著者: Chung, Ki Wung, Dhillon, Poonam, Huang, Shizheng, Sheng, Xin, Shrestha, Rojesh, Qiu, Chengxiang, Kaufman, Brett A., Park, Jihwan, Pei, Liming, Baur, Joseph, Palmer, Matthew, Susztak, Katalin
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054893/
https://ncbi.nlm.nih.gov/pubmed/31474566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.08.003
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料