The Effect of CpG Sequences on Capsid-Specific CD8(+) T Cell Responses to AAV Vector Gene Transfer

Transfer of genes by adeno-associated virus (AAV) vectors is benefiting patients with particular genetic defects. Challenges remain by rejection of AAV-transduced cells, which may be caused by CD8(+) T lymphocytes directed to AAV capsid antigens. Reducing the number of CpG motifs from the genome of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Xiang, ZhiQuan, Kurupati, Raj K., Li, Yan, Kuranda, Klaudia, Zhou, Xiangyang, Mingozzi, Federico, High, Katherine A., Ertl, Hildegund C.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2020
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054717/
https://ncbi.nlm.nih.gov/pubmed/31839483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.11.014
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller